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Lambert Eaton Myasthenic Syndrome Definition
This post contains definition of Lambert Eaton Myasthenic Syndrome which also called lambert-eaton myopathic-myasthenic syndrome, lambert-eaton myasthenic-myopathic syndrome, lambert eaton syndrome, eaton-lambert myopathic-myasthenic syndrome, eaton-lambert myasthenic-myopathic syndrome, eaton lambert syndrome, eaton lambert myasthenic syndrome, myopathic-myasthenic syndrome of lambert-eaton, myopathic myasthenic syndrome of eaton lambert, myasthenic myopathic syndrome of lambert eaton, myasthenic myopathic syndrome of eaton lambert. Make sure to bookmark this post so you don't lose this in the future.
An autoimmune disease characterized by weakness and fatigability of proximal muscles, particularly of the pelvic girdle, lower extremities, trunk, and shoulder girdle. There is relative sparing of extraocular and bulbar muscles. CARCINOMA, SMALL CELL of the lung is a frequently associated condition, although other malignancies and autoimmune diseases may be associated. Muscular weakness results from impaired impulse transmission at the NEUROMUSCULAR JUNCTION. Presynaptic calcium channel dysfunction leads to a reduced amount of acetylcholine being released in response to stimulation of the nerve. (From Adams et al., Principles of Neurology, 6th ed, pp 1471)
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